Research has shown that an extract from Rosa gallica strikingly increases the effectiveness of several antibiotics against methicillin-resistant Staphylococcus aureus. Two active compounds from the extract have been identified as tellimagrandin I and rugosin B. Other studies have demonstrated strong activity of Rosa gallica extract against strains of Candida albicans isolated from overtreatment with antibiotics. Additionally, the effect of an anthocyanin preparation isolated from the flower petals of Rosa gallica demonstrated strong effects of Rosa extracts against abnormal cells. A five year research study by Dr. Bard’s Biofoundation for Angiogenesis Research and Development preceded the development of the chemical constituents of the Pro Rose Plus formulation. Scientific evaluation has shown the antioxidant effect to be ten times more powerful than green tea preparations and resveratrol formulations.
Use of oral antioxidants such as Pro Rose Plus have been observed to promote collagen regeneration, visible with high resolution sonograms and special laser exams called optical coherent tomography (OCT). Likewise, improved blood flow to hair follicles has been demonstrated with vascular imaging technologies. The 2012 World Antiaging Conference and the 2013 World Liposurgery Conference showed poor dermal penetration of creams but good tissue regeneration with internal absorption of orally taken antioxidants.